There’s nothing quite like hitting the open road—the windows down, your favorite playlist blasting, and the promise of new adventures ahead. But you don’t need weeks off to enjoy an epic road trip. Whether you crave coastal views, mountain escapes, or charming small towns, these weekend-friendly US road trips will leave you refreshed, inspired, and ready for Monday.

1. Pacific Coast Highway, California
Route: San Francisco to Big Sur (or vice versa)
The Pacific Coast Highway (PCH) is a short but iconic stretch of California coastline that feels like a postcard at every turn. In just a few hours, you’ll encounter stunning cliffside views, golden beaches, and charming seaside towns.

• Must-Stop: Big Sur’s Bixby Creek Bridge for a photo op and McWay Falls in Julia Pfeiffer Burns State Park.

• Food Tip: Grab a seafood lunch in Monterey or stop for coffee in Carmel-by-the-Sea.

2. Blue Ridge Parkway, North Carolina to Virginia
Route: Asheville, NC to Roanoke, VA
Known as “America’s Favorite Drive,” the Blue Ridge Parkway offers jaw-dropping views of the Appalachian Mountains. Perfect for nature lovers, this winding road is dotted with scenic overlooks, waterfalls, and hiking trails.

• Must-Stop: Linville Falls for an easy hike and Mabry Mill for a slice of history and homemade biscuits.

• Best Time: Fall, when the leaves transform into a vibrant sea of red, orange, and gold.

3. Route 66: Chicago to St. Louis
Route: Chicago, IL to St. Louis, MO
Kick off a bite-sized piece of the legendary Route 66 with this weekend road trip. From quirky roadside attractions to historic diners, you’ll feel like you’ve stepped back in time.

• Must-Stop: The Gemini Giant in Wilmington, IL and the Route 66 Museum in Pontiac, IL.

• Food Tip: Stop for a classic Route 66 burger at Lou Mitchell’s in Chicago or Ted Drewes Frozen Custard in St. Louis.

4. Florida Keys: Miami to Key West
Route: Miami, FL to Key West, FL
The drive through the Florida Keys is short but unforgettable. This route takes you over 42 bridges surrounded by crystal-clear turquoise water, with each island offering its own charm.

• Must-Stop: The Seven Mile Bridge for jaw-dropping views and Bahia Honda State Park for swimming or lounging.

• Pro Tip: End your trip with a sunset toast at Mallory Square in Key West.

5. Cascade Loop, Washington State
Route: Start in Seattle, WA and loop through the North Cascades
This underrated gem of a road trip offers a little bit of everything: snow-capped mountains, alpine lakes, and charming small towns. It’s a perfect escape from city life into the Pacific Northwest’s natural beauty.

• Must-Stop: Leavenworth, a Bavarian-inspired village, and Diablo Lake for its Instagram-worthy turquoise water.

• When to Go: Late spring through fall for the best driving conditions and views.

6. New England Charm: Boston to Woodstock, Vermont
Route: Boston, MA to Woodstock, VT
If you’re craving picturesque small towns and rolling countryside, this road trip delivers. The journey from Boston to Vermont is lined with charming villages, covered bridges, and maple syrup farms.

• Must-Stop: Quechee Gorge, the “Grand Canyon of the East,” and Woodstock’s cozy main street for shopping and local treats.

• Food Tip: Try fresh apple cider donuts at a roadside farm stand.